Medicinal and Synthetic Chemistry

Medicinal Chemistry

• Hit-to-lead medicinal chemistry and library synthesis for hit compound follow-up
• Design and synthesis of targeted analogs with improved potency, PK, and IP properties
• Synthesis of small numbers of hypothesis-driven compounds

Synthetic Chemistry

• Synthesis of probe, tool, and reference compounds
• Preparation of biotinylated and fluorescently labeled molecules

State of the art chemistry resources

• Waters Acquity-H UPLC/MS
• Cambridgesoft electronic lab notebooks
• Agilent A2Prep mass-directed prep HPLC for compound purification
• Biotage microwave reactor and flash purification system
• H-Cube flow hydrogenator

Northwestern and CBC institution rates are project specific. Please contact us for pricing.