Faculty

The Center faculty includes clinical and basic science investigators from Northwestern's Weinberg College of Arts and Sciences and Feinberg School of Medicine, University of Illinois' College of Medicine and the Biological Division at the University of Chicago.

Affiliated Faculty

Wayne Anderson
X-ray crystallographic analysis of protein-ligand interactions
Web Site
Michael J. Avram
Pharmacokinetics and pharmacodynamics of hypnotics, sedatives, opioids, analgesics, non-depolarizing neuromuscular blockers, chemotherapeutics
Web Site
Greg Beitel
Molecular genetics of organ morphogenesis
Web Site
Raymond Bergan
Pharmacologic regulation of cell adhesion
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Lester (Skip) Binder
Microtubule proteins, fibrillar pathology in neurodegenerative disease
Web Site
Paul Bryce
Nischarin as a target for drug development for anaphylaxis
Web Site
Irina Budunova
Alteration of cell signaling during tumorigenesis as the basis for the development of new approaches to prevention and treatment of cancer
Web Site
John Crispino
Transcriptional regulation of normal and malignant blood cell development
Web Site
John Disterhoft
Cellular mechanisms and pharmacological enhancement of learning in young and aging brain
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Elizabeth Eklund
Leukemia, Lymphoma, Myeloma
Web Site
David Engman
Biology of parasitic diseases; Pathogenesis and treatment of myocarditis
Web Site
Sui Huang
The perinucleolar compartment and malignant transformation
Web Site
Michael Jewett
Cell-Free Systems and Synthetic Biology
Web Site
William Karpus
Role of chemokines and cytokines in autoimmunity
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William Klein
Cell and structural biology of Alzheimer’s disease; memory-linked synapse structure and signal transduction
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Carole LaBonne
Development of the vertebrate neural crest
Web Site
Robert Lamb
Viral glycoproteins, ion channels, and RNA-binding proteins
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Brian Layden
Identification of selective small molecules agonists for the GPCR target FFAR2 (GPR43) through in-silico docking
Web Site
Richard Longnecker
Epstein-Barr virus transformation, latency and entry
Web Site
Thomas Lukas
Signal transduction, proteomics, systems biology, neurodegenerative disease, vascular disease
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Andrew Mazar
Cancer, pulmonary and neurodegnerative translational medicine
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Thomas Meade
Inorganic coordination chemistry; bioinorganic chemistry, and molecular imaging
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Marsel Mesulam
Cholinergic pathways, cognitive mapping, Alzheimer's disease
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Richard Miller
Neural ion channels; neuronal death mechanisms
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Stephen Miller
Regulation of T-cell immune responses, autorimmune disease models of multiple sclerosis
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Alfonso Mondragon
DNA topoisomerases & proteins that modify DNA topology; RNA structure/function, spectrin & related proteins
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Richard Morimoto
Molecular response to stress, protein folding quality control, misfolded proteins & neurodegenerative diseases
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Sonbinh Nguyen
Inorganic/organometaollic chemistry, organic synthesis, polymer science, environmental friendly catalysis and biomaterials
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Thomas O'Halloran
Chemistry and biology of transition metals and metalloproteins
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Leonidas Platanias
chronic leukemias, multiple myeloma, non-hodgkin's lymphoma
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Sarah Rice
Structural mechanisms for molecular motor function and regulation
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Steven Rosen
Hormonal therapies of cancer and resistance mechanisms
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Karl Scheidt
New organic reaction development and the synthesis of molecules with interesting biological and structural attributes
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Mala Shanmugam
HIV Protease Inhibitor Pharmacophore Based Development of GLUT4 Targeting Compounds for the Treatment of Multiple Myeloma and GLUT4-Dependent Malignancies
Web Site
Teepu Siddique
Molecular basis of neurodegeneration and amyotrophic lateral sclerosis
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Richard Silverman
Design/synthesis of enzyme inhibitors; mechanisms of enzyme inactivation; enzyme-adduct structures
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Erik Sontheimer
Noncoding RNAs in Gene Regulation
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Alexander Statsuk
Chemical biology, protein degradation pathways, cancer
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D. James Surmeier
Modulation of neuronal excitability
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Regan Thomson
Synthesis and application of natural products to medicinal and biological problems, especially cancer and neurodegenerative disorders
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Robert Vassar
Secretases and animal models of Alzheimer's disease
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Douglas Vaughan
Plasminogen activator system in cardiovascular disease
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Mark Wainwright
Mechanisms of acute brain injury in children
Web Site
D.Martin Watterson
Signal transduction pathways as drug discovery targets
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Eric Weiss
Signaling Pathways in the Control of Cell Architecture
Web Site
Gayle Woloschak
Nanocomposites; Genes controlling radiosensitivity and motor neuron dysfunction
Web Site
Teresa Woodruff
Hormonal Control of the Reproductive Axis by Inhibin
Web Site
Phyllis Zee
Aging and the circadian clock system; genetics of sleep disorders
Web Site

 

CMIDD is an affiliate center of the Chemistry of Life Processes Institute at Northwestern University.
Center for Molecular Innovation and Drug Discovery, 2170 Campus Dr., Evanston, IL 60208-3113 | Contact: drugdiscovery@northwestern.edu
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